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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62445 | Tubulin inhibitor 22 | ||
Tubulin inhibitor 22 (compound 4c) is a potent inhibitor of tubulin that exhibits anti-angiogenic and anti-cancer activity. tubulin inhibitor 22 blocks the cell cycle of MGC-803 cells in the G2/M phase. tubulin inhibitor... | |||
T3S0209 | Vincristine | ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR | |
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato... | |||
T1270 | Vincristine sulfate | Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate | Apoptosis , Microtubule Associated |
Vincristine sulfate (Leurocristine sulfate) binds irreversibly to microtubules and spindle proteins in S phase and interferes the formation of the mitotic spindle. | |||
T60735 | Tubulin polymerization-IN-22 | ||
Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase as well as induces apoptosis. Tubulin polymerization-IN-22 is an inhibitor of tubulin polymerization (IC 50 = 8.1 μM) [1]. | |||
T63822 | VEGFR-2-IN-22 | ||
VEGFR-2-IN-22 (Compound 25) is an inhibitor of VEGFR-2 and β-tubulin polymerization with an IC50=19.82 nM for VEGFR-2. VEGFR-2-IN-22 is capable of inducing apoptosis. |